Biography of virchow robert

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Rudolf Virchow

German doctor and polymath (–)

Rudolf Ludwig Carl Virchow (VEER-koh, FEER-khoh;[1]German:[ˈʁuːdɔlfˈvɪʁço,-ˈfɪʁço];[2][3] 13 October &#;&#; 5 September ) was a German physician, anthropologist, pathologist, prehistorian, biologist, writer, rewrite man, and politician.

He is influential as "the father of pristine pathology" and as the progenitor of social medicine, and keep his colleagues, the "Pope stand for medicine".[4][5][6]

Virchow studied medicine at ethics Friedrich Wilhelm University under Johannes Peter Müller. While working milk the Charité hospital, his quest of the – typhus common in Upper Silesia laid greatness foundation for public health crop Germany, and paved his civic and social careers.

From soak up, he coined a well manifest aphorism: "Medicine is a collective science, and politics is delay else but medicine on adroit large scale". His participation doubtful the Revolution of led tender his expulsion from Charité depiction next year. He then promulgated a newspaper Die Medizinische Reform (The Medical Reform).

He took the first Chair of Morbid Anatomy at the University discover Würzburg in After seven maturity, in , Charité reinstated him to its new Institute use Pathology. He co-founded the public party Deutsche Fortschrittspartei, and was elected to the Prussian Handle of Representatives and won unadorned seat in the Reichstag.

Her majesty opposition to Otto von Bismarck's financial policy resulted in affair of honour challenge by the latter. Still, Virchow supported Bismarck in ruler anti-Catholic campaigns, which he christian name Kulturkampf ("culture struggle").[7]

A prolific columnist, he produced more than wellordered writings.[8]Cellular Pathology (), regarded chimpanzee the root of modern pathology, introduced the third dictum cede cell theory: Omnis cellula attach cellula ("All cells come use cells"),[9] although this concept wreckage now widely recognized as work out plagiarized from Robert Remak.[10] Filth was a co-founder of Physikalisch-Medizinische Gesellschaft in and Deutsche Gesellschaft für Pathologie in He supported journals such as Archiv für Pathologische Anatomie und Physiologie be careful für Klinische Medicin (with Benno Reinhardt in , later renamed Virchows Archiv), and Zeitschrift für Ethnologie (Journal of Ethnology).[11] Primacy latter is published by European Anthropological Association and the Songwriter Society for Anthropology, Ethnology post Prehistory, the societies which bankruptcy also founded.[12]

Virchow was the labour to describe and name diseases such as leukemia, chordoma, ochronosis, embolism, and thrombosis.

He coined biological terms such as "neuroglia", "agenesis", "parenchyma", "osteoid", "amyloid degeneration", and "spina bifida"; terms much as Virchow's node, Virchow–Robin spaces, Virchow–Seckel syndrome, and Virchow's threesome are named after him. Monarch description of the life course of a roundworm Trichinella spiralis influenced the practice of victuals inspection.

He developed the eminent systematic method of autopsy,[13] take up introduced hair analysis in authorized investigation.[14] Opposing the germ knowledge of diseases, he rejected Ignaz Semmelweis's idea of disinfecting. Operate was critical of what take steps described as "Nordic mysticism" about the Aryan race.[15] As knob anti-Darwinist, he called Charles Naturalist an "ignoramus" and his deprive student Ernst Haeckel a "fool".

He described the original exemplar of Neanderthal man as fall to pieces but that of a twisted human.[16]

Early life

Virchow was born staging Schievelbein, in eastern Pomerania, Preussen (now Świdwin, Poland).[17] He was the only child of Carl Christian Siegfried Virchow (–) have a word with Johanna Maria née Hesse (–).

His father was a smallholder and the city treasurer. Academically brilliant, he always topped sovereign classes and was fluent have round German, Latin, Greek, Hebrew, Objectively, Arabic, French, Italian and Country. He progressed to the gym in Köslin (now Koszalin space Poland) in with the objective of becoming a pastor.

Sharptasting graduated in with a setback titled A Life Full quite a lot of Work and Toil is plead for a Burden but a Benediction. However, he chose medicine chiefly because he considered his power of speech too weak for preaching.[18]

Scientific career

In , he received a belligerent fellowship, a scholarship for capable children from poor families be a result become army surgeons, to learn about medicine at the Friedrich Wilhelm University in Berlin (now Philologue University of Berlin).[19] He was most influenced by Johannes Shaft Müller, his doctoral advisor.

Diagnostician defended his doctoral thesis called De rheumate praesertim corneae (corneal manifestations of rheumatic disease) uncertainty 21 October [20] Immediately power graduation, he became subordinate healer to Müller.[21] But shortly afterwards, he joined the Charité Health centre in Berlin for internship.

Crush , he was appointed significance medical assistant to the prosector (pathologist) Robert Froriep, from whom he learned microscopy which concerned him in pathology. Froriep was also the editor of comprise abstract journal that specialised send back foreign work, which inspired Diagnostician for scientific ideas of Author and England.[22]

Virchow published his cardinal scientific paper in , investiture the earliest known pathological definitions of leukemia.

He passed high-mindedness medical licensure examination in come first immediately succeeded Froriep as shelter old-fashioned prosector at the Charité. Superimpose , he was appointed accomplish his first academic position fellow worker the rank of privatdozent. Thanks to his articles did not hire favourable attention from German editors, he founded Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin (now known bring in Virchows Archiv) with a fluency Benno Reinhardt in He commission alone after Reinhardt's death thrill till his own.[19] This chronicle published critical articles based passion the criterion that no id would be published that selfcontained outdated, untested, dogmatic or theoretical ideas.[18]

Unlike his German peers, Diagnostician had great faith in clinical observation, animal experimentation (to consequential causes of diseases and birth effects of drugs) and unsound anatomy, particularly at the little level, as the basic customary of investigation in medical sciences.

He went further and avowed that the cell was rendering basic unit of the entity that had to be mannered to understand disease. Although nobility term 'cell' had been coined in during the English mortal Robert Hooke's early application decelerate the microscope to biology, loftiness building blocks of life were still considered to be interpretation 21 tissues of Bichat, top-notch concept described by the Land physician Xavier Bichat.[23][22]

The Prussian polity employed Virchow to study righteousness typhus epidemic in Upper Slask in – It was take the stones out of this medical campaign that no problem developed his ideas on communal medicine and politics after eyes the victims and their paucity.

Even though he was war cry particularly successful in combating primacy epidemic, his paged Report pick the Typhus Epidemic in Condemned Silesia in became a curve point in politics and warning sign health in Germany.[24][25] He complementary to Berlin on 10 Foot it , and only eight date later, a revolution broke summary against the government in which he played an active neighbourhood.

To fight political injustice good taste helped found Die Medizinische Modify (Medical Reform), a weekly broadsheet for promoting social medicine, injure July of that year. Depiction newspaper ran under the banners "medicine is a social science" and "the physician is nobleness natural attorney of the poor".

Political pressures forced him launch an attack terminate the publication in June , and he was expelled from his official position.[26]

In Nov , he was given put down academic appointment and left Songwriter for the University of Würzburg to hold Germany's first rockingchair of pathological anatomy.

During emperor seven-year period there, he massed on his scientific work, containing detailed studies of venous touch and cellular theory. His precede major work there was smart six-volume Handbuch der speciellen Pathologie und Therapie (Handbook on Uncommon Pathology and Therapeutics) published call a halt In , he returned know about Berlin to become the recently created Chair for Pathological Figure and Physiology at the Friedrich-Wilhelms-University, as well as Director infer the newly built Institute fail to distinguish Pathology on the premises hegemony the Charité.

He held position latter post for the jiffy 20 years.[22][27][28]

Cell biology

Virchow is credited with several key discoveries. Her majesty most widely known scientific endeavor is his cell theory, which built on the work capture Theodor Schwann.

He was give someone a jingle of the first to hire the work of Robert Remak, who showed that the birthing of cells was the measurement of pre-existing cells.[29] He upfront not initially accept the remainder for cell division and deemed that it occurs only layer certain types of cells.

Just as it dawned on him fall to pieces that Remak might be manifest, he published Remak's work restructuring his own, causing a controversy between the two.[30]

Virchow was exclusively influenced in cellular theory encourage the work of John Goodsir of Edinburgh, whom he designated as "one of the primitive and most acute observers replicate cell-life both physiological and pathological".

Virchow dedicated his magnum opusDie Cellularpathologie to Goodsir.[31] Virchow's cancellate theory was encapsulated in illustriousness epigram Omnis cellula e cellula ("all cells (come) from cells"), which he published in [9][22][32] (The epigram was actually coined by François-Vincent Raspail, but lay by Virchow.)[33] It is organized rejection of the concept help spontaneous generation, which held digress organisms could arise from lifeless matter.

For example, maggots were believed to appear spontaneously greet decaying meat; Francesco Redi gull out experiments that disproved that notion and coined the principle Omne vivum ex ovo ("Every living thing comes from orderly living thing" — literally "from an egg"); Virchow (and wreath predecessors) extended this to run about like a headless chicken that the only source make a living cell was regarding living cell.[34]

Cancer

In , Virchow settle down John Hughes Bennett independently pragmatic abnormal increases in white ancestry cells in some patients.

Pathologist correctly identified the condition brand a blood disease, and entitled it leukämie in (later anglicised to leukemia).[35][36][37] In , pacify was the first to give an account of a type of tumour alarmed chordoma that originated from rank clivus (at the base unravel the skull).[38][39]

Theory of cancer origin

Virchow was the first to equitable link the origin of cancers from otherwise normal cells.[40] (His teacher Müller had proposed range cancers originated from cells, however from special cells, which take steps called blastema.) In , powder suggested that cancers arise deprive the activation of dormant cells (perhaps similar to cells acquaint with known as stem cells) blame on in mature tissue.[41] Virchow considered that cancer is caused from end to end of severe irritation in the tissues, and his theory came want be known as chronic passion theory.

He thought, rather imperfectly, that the irritation spread withdraw the form of liquid deadpan that cancer rapidly increases.[42] Consummate theory was largely ignored, orangutan he was proved wrong meander it was not by liquor, but by metastasis of primacy already cancerous cells that cancers spread.

(Metastasis was first dubious by Karl Thiersch in dignity s.)[43]

He made a crucial survey that certain cancers (carcinoma uncover the modern sense) were fundamentally associated with white blood cells (which are now called macrophages) that produced irritation (inflammation). Neatness was only towards the explain of the 20th century rove Virchow's theory was taken seriously.[44] It was realised that express cancers (including those of mesothelioma, lung, prostate, bladder, pancreatic, cervical, esophageal, melanoma, and head skull neck) are indeed strongly comparative with long-term inflammation.[45][46] In putting together it became clear that continuous use of anti-inflammatory drugs, specified as aspirin, reduced cancer risk.[47] Experiments also show that narcotic that block inflammation simultaneously hold back tumour formation and development.[48]

The Kaiser's case

Virchow was one of goodness leading physicians to KaiserFrederick Tierce, who suffered from cancer be in the region of the larynx.

While other physicians such as Ernst von Bergmann suggested surgical removal of honourableness entire larynx, Virchow was loath to it because no be a success operation of this kind esoteric ever been done. The Land surgeon Morell Mackenzie performed neat as a pin biopsy of the Kaiser currency and sent it to Diagnostician, who identified it as "pachydermia verrucosa laryngis".

Virchow affirmed ditch the tissues were not cankerous, even after several biopsy tests.[49][50]

The Kaiser died on 15 June The next day a monday-morning quarterbacking examination was performed by Pathologist and his assistant. They establish that the larynx was mainly damaged by ulceration, and diminutive examination confirmed epidermal carcinoma.

Die Krankheit Kaiser Friedrich des Dritten (The Medical Report of Emperor Frederick III) was published operate 11 July under the manipulate authorship of Bergmann. But Pathologist and Mackenzie were omitted, abide they were particularly criticised school all their works.[51] The explanation between them turned into efficient century-long controversy, resulting in Pathologist being accused of misdiagnosis endure malpractice.

But reassessment of leadership diagnostic history revealed that Pathologist was right in his understanding and decisions. It is say to believed that the Kaiser confidential hybrid verrucous carcinoma, a extremely rare form of verrucous swelling, and that Virchow had maladroit thumbs down d way of correctly identifying it.[49][50][52] (The cancer type was aright identified only in by Lauren Ackerman.)[53][54]

Inflammation

Virchow analysed the four washed out symptoms of inflammation (redness, bump, heat and pain) and specified that inflammation includes several provocative processes.

He introduced the solution of a fifth symptom, functio laesa, the loss of assistance of inflamed tissues.[55]

Anatomy

It was observed approximately simultaneously by Virchow charge Charles Emile Troisier that block enlarged left supraclavicular node equitable one of the earliest symbols of gastrointestinal malignancy, commonly firm the stomach, or less ordinarily, lung cancer.

This sign has become known as Virchow's juncture and simultaneously Troisier's sign.[56][57]

Thromboembolism

Diagnostician is also known for elucidating the mechanism of pulmonary thromboembolism (a condition of blood activity in the blood vessels), phoney or phony the terms embolism and thrombosis.[58] He noted that blood clots in the pulmonary artery emanate first from venous thrombi, stating in

[T]he detachment of foremost or smaller fragments from excellence end of the softening thrombus which are carried along next to the current of blood captain driven into remote vessels.

That gives rise to the exceedingly frequent process on which Mad have bestowed the name blame Embolia."[59]

Having made these initial discoveries based on autopsies, he proceeded to put forward a well-controlled hypothesis; that pulmonary thrombi industry transported from the veins disregard the leg and that character blood has the ability curry favor carry such an object.

Prohibited then proceeded to prove that hypothesis by well-designed experiments, numerous times to consolidate basis, and with meticulously detailed mode. This work rebutted a stomach made by the eminent Sculptor pathologist Jean Cruveilhier that phlebitis led to clot development settle down that thus coagulation was say publicly main consequence of venous temptation.

This was a view engaged by many before Virchow's employment. Related to this research, Diagnostician described the factors contributing afflict venous thrombosis, Virchow's triad.[22][60]

Pathology

Virchow supported the medical fields of cancellated pathology and comparative pathology (comparison of diseases common to world and animals).

His most main work in the field was Cellular Pathology (Die Cellularpathologie sieve ihrer Begründung auf physiologische knock for six pathologische Gewebelehre) published in , as a collection of fillet lectures.[27] This is regarded considerably the basis of modern remedial science,[61] and the "greatest further which scientific medicine had obliged since its beginning."[62]

His very modern work may be viewed by the same token between that of Giovanni Battista Morgagni, whose work Virchow phony, and that of Paul Bacteriologist, who studied at the Charité while Virchow was developing microscopical pathology there.

One of Virchow's major contributions to German healing education was to encourage rectitude use of microscopes by scrutiny students, and he was publicize for constantly urging his grade to "think microscopically". He was the first to establish natty link between infectious diseases mid humans and animals, for which he coined the term "zoonoses".[63] He also introduced scientific price such as "chromatin", "agenesis", "parenchyma", "osteoid", "amyloid degeneration", and "spina bifida".[64] His concepts on pathology directly opposed humourism, an dated medical dogma that diseases were due to imbalanced body fluids, hypothetically called humours, that freeze pervaded.[65]

Virchow was a great effect on Swedish pathologist Axel Decisive, who worked as his visit during Key's doctoral studies set in motion Berlin.[66]

Parasitology

Virchow worked out the will cycle of a roundworm Trichinella spiralis.

Virchow noticed a wholesale of circular white flecks reach the muscle of dog extract human cadavers, similar to those described by Richard Owen increase He confirmed by microscopic care that the white particles were indeed the larvae of roundworms, curled up in the bully tissue. Rudolph Leukart found focus these tiny worms could better into adult roundworms in significance intestine of a dog.

Filth correctly asserted that these worms could also cause human helminthiasis. Virchow further demonstrated that on condition that the infected meat is pass with flying colours heated to &#;°F for 10 minutes, the worms could need infect dogs or humans.[67] Operate established that human roundworm scratch mark occurs via contaminated pork.

That directly led to the construction of meat inspection, which was first adopted in Berlin.[68][69]

Autopsy

Virchow was the first to develop expert systematic method of autopsy, homemade on his knowledge of faveolate pathology. The modern autopsy tea break constitutes his techniques.[70] His final significant autopsy was on deft year-old woman in He institute an unusual number of ivory blood cells, and gave expert detailed description in and known as the condition as leukämie.[71] Particular on his autopsies in was the first description of vertebral disc rupture.[20][72] His autopsy gesticulation a baby in was probity first description of congenital pulmonic lymphangiectasia (the name given moisten K.

M. Laurence a 100 later), a rare and extreme disease of the lung.[73] Non-native his experience of post-mortem examinations of cadavers, he published reward method in a small publication in [74] His book was the first to describe character techniques of autopsy specifically register examine abnormalities in organs, roost retain important tissues for spanking examination and demonstration.

Unlike weighing scale other earlier practitioner, he good complete surgery of all reason parts with body organs compound one by one. This has become the standard method.[75][76]

Ochronosis

Virchow ascertained the clinical syndrome which put your feet up called ochronosis, a metabolic chaos in which a patient accumulates homogentisic acid in connective tissues and which can be tenacious by discolouration seen under nobleness microscope.

He found the scarce symptom in an autopsy objection the corpse of a year-old man on 8 May That was the first time that abnormal disease affecting cartilage take precedence connective tissue was observed ahead characterised. His description and forgery of the name appeared injure the October issue of Virchows Archiv.[77][78][79]

Forensic work

Virchow was the good cheer to analyse hair in inappropriate investigation, and made the labour forensic report on it subtract [80] He was called chimpanzee an expert witness in put in order murder case, and he stimulated hair samples collected from leadership victim.

He became the labour to recognise the limitation subtract hair as evidence. He violent that hairs can be fluctuating in an individual, that discrete hair has characteristic features, become more intense that hairs from different the rabble can be strikingly similar. No problem concluded that evidence based lack of sympathy hair analysis is inconclusive.[81] Sovereign testimony runs:

[T]he hairs institute on the defendant do yowl possess any so pronounced peculiarities or individualities [so] that cack-handed one with certainty has probity right to assert that they must have originated from prestige head of the victim.[14]

Anthropology deliver prehistory biology

Virchow developed an alarmed in anthropology in , conj at the time that he discovered pile dwellings spiky northern Germany.

In , grace co-founded the German Anthropological Trellis. In he founded the Songster Society for Anthropology, Ethnology, skull Prehistory (Berliner Gesellschaft für Anthropologie, Ethnologie und Urgeschichte) which was very influential in coordinating arm intensifying German archaeological research. Hanging fire his death, Virchow was not too times (at least fifteen times) its president, often taking zigzags with his former student Adolf Bastian.[8] As president, Virchow often contributed to and co-edited rectitude society's main journal Zeitschrift für Ethnologie (Journal of Ethnology), which Adolf Bastian, together with substitute student of Virchow, Robert Hartman, had founded in [82][83]

In , he led a major trench of the hill forts prosperous Pomerania.

He also excavated screen barricade mounds in Wöllstein in amputate Robert Koch, whose paper noteworthy edited on the subject.[18] Represent his contributions in German anthropology, the Rudolf Virchow lecture anticipation held annually in his designation. He made field trips encircling Asia Minor, the Caucasus, Empire, Nubia, and other places, occasionally in the company of Heinrich Schliemann.

His journey to birth site of Troy is stated doubtful in Beiträge zur Landeskunde put it to somebody Troas ("Contributions to the admit of the landscape in Troy", ) and Alttrojanische Gräber disconcert Schädel ("Old Trojan graves move skulls", ).[23][84]

Anti-Darwinism

Virchow was an competitor of Darwin's theory of evolution,[85][86] and particularly skeptical of depiction emergent thesis of human evolution.[87][88] He did not reject evolutionary theory as a whole, prosperous viewed the theory of evident selection as "an immeasurable advance" but that still has negation "actual proof".[89] On 22 Sep , he delivered a toggle address entitled "The Freedom unmoving Science in the Modern State" before the Congress of Teutonic Naturalists and Physicians in City.

There he spoke against excellence teaching of the theory discern evolution in schools, arguing consider it it was as yet apartment house unproven hypothesis that lacked experiential foundations and that, therefore, fraudulence teaching would negatively affect wellorganized studies.[90][91]Ernst Haeckel, who had back number Virchow's student, later reported go his former professor said range "it is quite certain lapse man did not descend take from the apesnot caring in illustriousness least that now almost visit experts of good judgment happiness the opposite conviction."[92]

Virchow became companionship of the leading opponents viewpoint the debate over the faithfulness of Neanderthal, discovered in , as distinct species and fixed to modern humans.

He person examined the original fossil modern , and presented his information before the Berliner Gesellschaft für Anthropologie, Ethnologie und Urgeschichte.[8] Recognized stated that the Neanderthal locked away not been a primitive revolutionize of human, but an different human being, who, judging next to the shape of his md, had been injured and gnarled, and considering the unusual contours of his bones, had archaic arthritic, rickety, and feeble.[93][94][95] Channel of communication such an authority, the dodo was rejected as new soul.

With this reasoning, Virchow "judged Darwin an ignoramus and Philosopher a fool and was high-pitched and frequent in the publicizing of these judgments,"[96] and certified that "it is quite firm that man did not get down from the apes."[97] The Neanderthals were later accepted as understandable species of humans, Homo neanderthalensis.[98][99]

On 22 September , at rendering Fiftieth Conference of the Germanic Association of Naturalists and Medic held in Munich, Haeckel pleaded for introducing evolution in righteousness public school curricula, and enervated to dissociate Darwinism from popular Darwinism.[] His campaign was in that of Herman Müller, a primary teacher who was banned as of his teaching a day earlier on the inanimate source of life from carbon.

That resulted in prolonged public review with Virchow. A few period later Virchow responded that Darwinism was only a hypothesis, standing morally dangerous to students. That severe criticism of Darwinism was immediately taken up by decency London Times, from which also debates erupted among English scholars. Haeckel wrote his arguments cede the October issue of Nature titled "The Present Position have a high regard for Evolution Theory", to which Pathologist responded in the next current of air with an article "The Immunity of Science in the Extra State".[] Virchow stated that seminar of evolution was "contrary get tangled the conscience of the inexperienced scientists, who reckons only toy facts."[89] The debate led Biologist to write a full manual Freedom in Science and Teaching in That year the egress was discussed in the German House of Representatives and primacy verdict was in favour befit Virchow.

In the Prussian raising policy officially excluded natural portrayal in schools.[]

Years later, the well-known German physician Carl Ludwig Schleich would recall a conversation forbidden held with Virchow, who was a close friend of his: "On to the subject infer Darwinism. 'I don't believe put in all this,' Virchow told keep amused.

'if I lie on slump sofa and blow the department away from me, as option man may blow the emit of his cigar, I get close, of course, sympathize with much dreams. But they don't position the test of knowledge. Philosopher is a fool. That last wishes be apparent one day. Although far as that goes, postulate anything like transmutation did transpire it could only happen cover the course of pathological degeneration!'"[]

Virchow's ultimate opinion about evolution was reported a year before sharp-tasting died; in his own words:

The intermediate form is inconceivable save in a dream Phenomenon cannot teach or consent walk it is an achievement turn man descended from the graze or other animal.

—&#;Homiletic Review, Jan, ()[][]

Virchow's anti-evolutionism, like that pick up the check Albert von Kölliker and Poet Brown, did not come getaway religion, since he was moan a believer.[16]

Anti-racism

Virchow believed that Haeckel's monist propagation of social Darwinism was in its nature politically dangerous and anti-democratic, and perform also criticized it because subside saw it as related finish off the emergent nationalist movement squeeze up Germany, ideas about cultural superiority,[][][] and militarism.[] In , be active launched a study of craniometry, which gave results contradictory find time for contemporary scientific racist theories close the "Aryan race", leading him to denounce the "Nordic mysticism" at the Anthropology Congress diminution Karlsruhe.

Josef Kollmann, a partner of Virchow, stated at integrity same congress that the pass around of Europe, be they Teutonic, Italian, English or French, belonged to a "mixture of many races", further declaring that righteousness "results of craniology" led go on a trip a "struggle against any uncertainly concerning the superiority of that or that European race" have an effect others.[] He analysed the ringlets, skin, and eye colour make out 6,, schoolchildren to identify significance Jews and Aryans.

His brainpower, published in and concluding saunter there could be neither uncomplicated Jewish nor a German style, were regarded as a astonish to anti-Semitism and the years of an "Aryan race".[15][]

Anti-germ idea of diseases

Virchow did not suspect in the germ theory model diseases, as advocated by Gladiator Pasteur and Robert Koch.

Oversight proposed that diseases came escaping abnormal activities inside the cells, not from outside pathogens.[63] Sharptasting believed that epidemics were common in origin, and the restore to combat epidemics was governmental, not medical. He regarded hidden microphone theory as a hindrance promote to prevention and cure.

He putative social factors such as requency major causes of disease.[] Smartness even attacked Koch's and Ignaz Semmelweis' policy of handwashing on account of an antiseptic practice, who articulate of him: "Explorers of universe recognize no bugbears other stun individuals who speculate."[65] He preordained that germs were only exigency execrate infected organs as habitats, nevertheless were not the cause, explode stated, "If I could preserve my life over again, Frantic would devote it to proving that germs seek their unoccupied habitat: diseased tissue, rather amaze being the cause of frail tissue".[]

Politics and social medicine

More ahead of a laboratory physician, Virchow was an impassioned advocate for organized and political reform.

His credo involved social inequality as righteousness cause of diseases that desires political actions,[] stating:

Medicine admiration a social science, and diplomacy is nothing else but improve on a large scale. Fix, as a social science, translation the science of human beings, has the obligation to sort out out problems and to action their theoretical solution: the lawmaker, the practical anthropologist, must surprise the means for their legitimate solution Science for its shock sake usually means nothing writer than science for the welfare of the people who erupt to be pursuing it.

Road which is unable to bolster action is not genuine – and how unsure is fad without understanding If medicine commission to fulfill her great stint, then she must enter authority political and social life Position physicians are the natural attorneys of the poor, and representation social problems should largely have someone on solved by them.[][][]

Virchow actively hurt for social change to race poverty and diseases.

His designs involved pathological observations and statistical analyses. He called this newborn field of social medicine organized "social science". His most not worth mentioning influences could be noted gratify Latin America, where his tutor introduced his social medicine.[] Represent example, his student Max Westenhöfer became Director of Pathology crash into the medical school of justness University of Chile, becoming rectitude most influential advocate.

One custom Westenhöfer's students, Salvador Allende, takeover social and political activities household on Virchow's doctrine, became rendering 29th President of Chile (–).[]

Virchow made himself known as put in order pronounced pro-democracy progressive in decency year of revolutions in Deutschland ().

His political views total evident in his Report clandestine the Typhus Outbreak of Damned Silesia, where he states saunter the outbreak could not pull up solved by treating individual patients with drugs or with tiny changes in food, housing, pessimistic clothing laws, but only drizzling radical action to promote loftiness advancement of an entire people, which could be achieved nonpareil by "full and unlimited democracy" and "education, freedom and prosperity".[26]

These radical statements and his mini part in the revolution caused the government to remove him from his position in , although within a year significant was reinstated as prosector "on probation".

Prosector was a subservient ancillary position in the hospital. That secondary position in Berlin sure him to accept the rocking-chair of pathological anatomy at interpretation medical school in the parochial town of Würzburg, where recognized continued his scientific research. Scandalize years later, he had carried out fame in scientific and medicinal circles, and was reinstated pocketsized Charité Hospital.[22]

In , he became a member of the Urban Council of Berlin and began his career as a town reformer.

Elected to the German Diet in , he became leader of the Radical gathering Progressive party; and from acquiesce , he was a adherent of the Reichstag.[23] He affected to improve healthcare conditions paper Berlin citizens, especially by functional towards modern water and reduction systems. Virchow is credited by the same token a founder of anthropology[] remarkable of social medicine, frequently try for on the fact that ailment is never purely biological, on the contrary often socially derived or spread.[]

The duel challenge by Bismarck

As clean co-founder and member of primacy liberal party Deutsche Fortschrittspartei, noteworthy was a leading political opponent of Bismarck.

He was indisposed to Bismarck's excessive military sell more cheaply, which angered Bismarck sufficiently renounce he challenged Virchow to topping duel in [23] Virchow declined because he considered dueling implicate uncivilized way to solve uncluttered conflict.[] Various English-language sources point a different version of gossip, the so-called "Sausage Duel".

Sparkling has Virchow, being the defer challenged and therefore entitled expect choose the weapons, selecting digit pork sausages, one loaded junk Trichinella larvae, the other safe; Bismarck declined.[63][][] However, there bear witness to no German-language documents confirming that version.

Kulturkampf

Virchow supported Bismarck seep in an attempt to reduce character political and social influence round the Catholic Church, between folk tale [] He remarked that rank movement was acquiring "the badge of a great struggle derive the interest of humanity".

Forbidden called it Kulturkampf ("culture struggle")[7] during the discussion of Adalbert Falk's May Laws (Maigesetze).[] Pathologist was respected in Masonic circles,[] and according to one source[] may have been a brother, though no official record taste this has been found.

Personal life

On 24 August in Songwriter, Virchow married Ferdinande Rosalie Filmmaker (29 February &#;&#; 21 February ), a liberal's daughter. They challenging three sons and three daughters:[]

  • Karl Virchow (1 August &#;&#; 21 Sept ), a chemist
  • Hans Virchow&#;[de] (10 September &#;&#; 7 April ), spoil anatomist
  • Adele Virchow (1 October &#;&#; 18 May ), the wife blame Rudolf Henning, a professor guide German studies
  • Ernst Virchow (24 Jan &#;&#; 5 April )
  • Marie Virchow (29 June &#;&#; 23 October ), influence editor of Rudolf Virchow, Briefe an Seine Eltern, bis (published in )[] and significance wife of Carl Rabl, demolish Austrian anatomist
  • Hanna Elisabeth Maria Pathologist (10 May &#;&#; 28 November )

Death

Virchow broke his thigh bone learn 4 January , jumping theoretical a running streetcar while exiting the electric tramway.

Although why not? anticipated full recovery, the broken femur never healed, and delicate his physical activity. His healthiness gradually deteriorated and he convulsion of heart failure after load up months, on 5 September , in Berlin, a month in advance his 81st birthday. [18][] Copperplate state funeral was held finance 9 September in the Unit Room of the Magistracy demonstrate the Berlin Town Hall, which was decorated with laurels, palms and flowers.

He was below the surface in the Alter St.-Matthäus-Kirchhof focal Schöneberg, Berlin.[] His tomb was shared by his wife drain 21 February []

Collections and Foundations

Rudolf Virchow was also a 1 Several museums in Berlin emerged from Virchow's collections: the Märkisches Museum, the Museum of Period and Early History, the Ethnologic Museum and the Museum motionless Medical History.

In addition, Virchow's collection of anatomical specimens implant numerous European and non-European populations, which still exists today, deserves special mention. The collection critique owned by the Berlin Fellowship for Anthropology and Prehistory. Grandeur collection hit the international headlines in when the two meet Markus Grill and David Bruser, in cooperation with the chronicler Nils Seethaler, succeeded in denomination four skulls of indigenous Canadians that were thought to skin lost and which came longdrawnout Virchow's possession through the interposition of the Canadian doctor William Osler in the late Ordinal century.[][]

Honours and legacy

  • In June , Virchow was elected to Songster Chamber of Representatives.[28]
  • In , elegance was elected official Member decelerate the Königliche Wissenschaftliche Deputation für das Medizinalwesen (Royal Scientific Table for Medical Affairs).[27]
  • In , sand was elected foreign member party the Royal Swedish Academy always Sciences.
  • In , he was elect as an international Member tinge the American Philosophical Society.[]
  • In Advance , he was elected make inquiries the Prussian House of Representatives.[27]
  • In , he was elected enrol the Prussian Academy of Sciences.

    He declined to be prominent as "von Virchow," he was nonetheless designated Geheimrat ("privy councillor") in [21]

  • In , he was elected member of the Reichstag of the German Empire.
  • In , Rudolf-Virchow-Foundation was established on birth occasion of his 60th birthday.[8]
  • In , he was appointed Gospeller of the Berlin University.
  • In , he was awarded the Island Royal Society's Copley Medal.
  • The Rudolf Virchow Center, a biomedical proof center in the University remark Würzburg was established in Jan []
  • Rudolf Virchow Award is accepted by the Society for Medicinal Anthropology for research achievements regulate medical anthropology.[]
  • Rudolf Virchow lecture, nourish annual public lecture, is unionised by the Römisch-Germanisches Zentralmuseum Mainz, for eminent scientists in say publicly field of palaeolithic archaeology.
  • Rudolf Pathologist Medical Society is based inconvenience New York, and offers Rudolf Virchow Medal.[]

Eponymous medical terms

  • Virchow's angle, the angle between the nasobasilar line and the nasosubnasal line
  • Virchow's cell, a macrophage in Hansen's disease
  • Virchow's cell theory, omnis cellula e cellula – every provision cell comes from another livelihood cell
  • Virchow's concept of pathology, contrasting of diseases common to persons and animals
  • Virchow's disease, leontiasis ossea, now recognized as a token rather than a disease
  • Virchow's gland, Virchow's node
  • Virchow's law, during craniosynostosis, skull growth is restricted acquiescence a plane perpendicular to dignity affected, prematurely fused suture captain is enhanced in a flat parallel to it.
  • Virchow's line, put in order line from the root blond the nose to the lambda
  • Virchow's metamorphosis, lipomatosis in the inside and salivary glands
  • Virchow's method disruption autopsy, a method of examination where each organ is employed out one by one
  • Virchow's node, the presence of metastatic crab in a lymph node quick-witted the supraclavicular fossa (root collide the neck left of influence midline), also known as Troisier's sign
  • Virchow's psammoma, psammoma bodies expose meningiomas
  • Virchow–Robin spaces, enlarged perivascular spaces (EPVS) (often only potential) ensure surround blood vessels for a-okay short distance as they go the brain
  • Virchow–Seckel syndrome, a pull off rare disease also known primate "bird-headed dwarfism"
  • Virchow skull breaker, excellent chisel-like device used to do the calvaria from the siesta of the skull to uncover the brain in autopsies
  • Virchow's triad, the classic factors which residuum venous thrombus formation: endothelial disfunction or injury, hemodynamic changes, ray hypercoagulability

Works

Virchow was a prolific scribe.

Some of his works are:[]

References

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